Fundaçao Manhiça/Manhiça Research Center (FM/CISM)

The Manhiça Research Centre (CISM), together with the Barcelona Institute for Global Health (ISGlobal), have greatly contributed to the translation of health research into public health policies through strategic collaborators in many research studies conducted over the last 20 years.

They lead the clinical trial in Manhiça (Mozambique) and will complement the consortium with its expertise in causes of death studies and minimally invasive autopsy techniques. The sub-study of cases of death will help to improve the knowledge of respiratory infections in HIV-infected infants with severe pneumonia.

Centro de Investigação em Saúde da Manhiça (CISM) was created in 1996 with the aim of boosting and conducting biomedical research in priority health areas. Since its creation, the Center has been developed following the orientation of a Bilateral Cooperation Program between the Governments of Mozambique and Spain and with the support of the Clinic Hospital of the University of Barcelona (via the Clinical Foundation for Biomedical Research).

In 2008, it was set up the Manhiça Foundation to strengthen CISM’s institutional capacities. Now, the foundation manages the CISM general administration and the scientific research programme.

The main areas of activity are as follows:

  • Developing a multidisciplinary research agenda in malaria, HIV/AIDS, tuberculosis, respiratory infections, enteropathogens, and maternal, infant and reproductive health, with the objective of improving health policies and programmes.
  • Building Mozambique’s national capacities for health research through a training programme for young researchers and exchanges with other centres.
  • Improving the quality of care provided by the National health system.



NELSON TEMBE Principal Investigator
After finishing his degree in Biology (2007), Nelson Tembe earned his PhD in Medical Sciences from the Karolinska Institute in Sweden (2016). He has extensive experience in the area of sexually transmitted diseases and molecular biology of HIV. From 2009 to July 2017, he worked in studies in preparation for clinical trials of HIV vaccines and also conducted clinical trials.

Since August 2017, Nelson Tembe is working at Manhiça Foundation/Centro de Investigação em Saúde da Manhiça (CISM). He holds a position as the coordinator of the Acute Respiratory Infection and Invasive Bacterial Disease research Area of CISM.

Justina Magalhães Bramug is a medical doctor at the Manhiça Hospital District
and a Junior Researcher at CISM (Manhiça Health Research Centre), where she participates in multiple studies aiming to improve the lives of children suffering from various infectious diseases.

See others


Servicio Madrileño de Salud (SERMAS) / Fundación para la Investigación Biomédica del Hospital Universitario 12 de Octubre (FI+12)

Université de Bordeaux (UBx)

Université de Bordeaux (UBx)


Institut National de la Santé et de la Recherche Médicale (INSERM)

Fondazione Penta Onlus (PENTA)

Fondazione Penta Onlus

Stichting Katholieke Universiteit – Radboud University Medical Centre

Stichting Katholieke Universiteit – Radboud University Medical Centre


Barcelona Institute for Global Health (ISGlobal)

University of Lincoln (UoL)

University of Lincoln (UoL)

Programme PAC–CI

Programme PAC–CI

LSTM logo

Liverpool School of Tropical Medicine/Malawi-Liverpool-Wellcome Trust Clinical Research Programme (LSTM/MLW)


Universidade Eduardo Mondlane/Hospital Central de Maputo (UEM/HCM)

Makerere University

Makerere University (MU)


HerpeZ Limited (HerpeZ)


University of Zimbabwe Clinical Research Centre (UZCHS-CTRC)